The Biomaterials and Biomechanics Department is seeking a Senior Research Associate to begin immediately. The successful candidate will be joining an enthusiastic and dynamic group. This position requires research performance consistent with the goals of the principal investigator, Carmem Pfeifer PhD. The Senior Research Associate will often lead others workflow and manage/coordinate broad efforts within the lab, requiring the ability to build teams and remain organized and efficient. The lab is very active, with the opportunities to publishing papers, submit grant proposals, present at technical meetings, and working with partners in both industry and university / government.
There are currently several areas of work within my lab which span within the broad field of biomaterials and include the following specific topic areas:
1. Tertiary methacrylamides and thiourethane additives as novel dental composites. This project responded to a request of application released by NIH-NIDCR to develop the new generation of dental composites (RFA-DE-13-001). The ultimate outcome expected of this multi-institution project is to double the service-life of current materials. Our group proposed to do so by synthesizing a new class of dental monomers, based on methacrylamides. We also proposed to harness our previous knowledge with pre-polymerized thiourethane additives and translate that technology into this new polymer network. We have several papers showing that thiol-terminated thiourethane additives are capable of reducing polymerization stress and increasing toughness in methacrylate networks. This work is being done in collaboration with chemistry labs at Portland State University and has been funded by NIH-NIDCR (1U01DE023756-01) for five years, and is currently on the fourth year. See NIH press release at http://t.co/pTmlTXwK2n.
2. Smart self-sterilizing materials for class V restorations. This project also responded to a request of application released by NIH-NIDCR (RFA-DE-16-007) to develop \u201cNovel or Enhanced Dental Restorative Materials for Class V Lesions. Our proposal, which was funded, deals with using carboxybetaine functionalized materials that are able to respond to the pH of the environment and switch between antifouling and antibacterial characteristics. This work is being done in collaboration with the oral microbiology lab led by Dr. Justin Merritt, who is going to supervise the biofilm growth and attachment aspects. Our lab will concentrate on designing and synthesizing these smart, responsive materials to improve the service-life of dental restorations. This has a great impact in the aging population, with many restorations near the gum needing to be replaced every year due to failures in the material. Other biomedical applications where antifouling/antibacterial properties are desirable can also benefit from these monomers.
PhD in relevant field OR
Master\u2019s degree in Organic Chemistry, Polymer Science, Chemical Engineering or related field and 5 years\u2019 experience
Wet lab, specifically in organic synthesis of small molecules
Organic synthesis, preferably in polymer chemistry
Polymerization of crosslinked networks
Spectroscopy (IR, NMR, UV-VIS, Mass spec)
Manuscript and grant writing experience
Strong English language skills (writing and speaking) are required
Ability and skills needed to design and synthesize new organic molecules
Ability to troubleshoot road blocks inherent to organic synthesis
Must work independently
Ability to manage teams and coordinate broad efforts
Attention to detail and good record-keeping are essential
Must be able to perform the essential functions of the position with or without accommodation
As the state's only health and research university, OHSU brings together patient care, research, education of the next generation of health care providers and scientists and community service to improve the health and well-being of all Oregonians.The university is a conduit for learning for more than 2,800 students, providing training to interns, residents and fellows in postgraduate medical and research. It is the only place in Oregon that grants doctoral degrees in medicine, dentistry and nursing. OHSU cares for more than 251,000 patients each year from around the region and takes a leadership role in contributing to solutions involving the health of the state and the nation, such as health care access and transparency, ethics and workforce shortage. Beyond providing critical health care services, quality education and cutting-edge research, OHSU also is a key economic and social force in the Northwest. With an annual operating budget of $2.06 billion and more than 14,000 employees, OHSU is Portland?s largest employer. Its size contributes to its ability to provide... many services and community support activities not found anywhere else in Oregon. For more information visit http://www.ohsu.edu/xd/about/index.cfm