Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The staff scientist will work on independent and collaborative projects developing adoptive T cell immunotherapy for viral driven malignancies within the Program in Immunology and Clinical Research Division at Fred Hutchinson Cancer Research Center in the Chapuis laboratory ( https://research.fhcrc.org/chapuis ). The successful applicant will employ strategies for cloning T cell receptors (TCRs) and genetic modification of human T cells with TCRs specific for antigens expressed by malignancies. In vitro studies using human T cells and in vivo murine models will be used to develop and test novel T cell therapies. The staff scientist will perform correlative studies to evaluate the transfer, persistence and function of antigen-specific T cells in human clinical trials of adoptive T cell immunotherapy.
The Program in Immunology is a leader in the development and clinical application of adoptive immunotherapy using genetically modified T cells and is committed to the advancement of this approach. The staff scientist may also participate in the laboratory evaluation of ongoing clinical trials involving engineering of peripheral blood stem cell grafts for improved allogeneic hematopoietic stem cell transplantation outcomes, and in the development of future immunotherapy strategies. This is a full-time position with excellent benefits.
At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.